The PEN-FAST+ score was developed to improve the PEN-FAST negative predictive value using these two additional criteria.
It can be used to select patients at low risk of an allergic reaction, particularly those with delayed hypersensitivity who could have a direct DPT without previous skin tests, for delabeling penicillin allergies.
The PEN-FAST+ score is externally validated using retrospective data. So far, no large prospective and multicentric study using PEN-FAST+ have been performed.
This algorithm is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.
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