Evidencio validations - Evidencio
Validation of a nomogram predicting sentinel lymph node status in melanoma in an Irish population
This nomogram is valid and accurate at predicting sentinel lymph node (SLN) positivity in an Irish population. This may facilitate the clinical decision to perform a SLN biopsy in malignant melanoma.
Research authors: J.F.C. Woods, J.A. de Marchi, A.J. Lowery, A.D.K. Hill
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Discrimination

Rows included 0
C-index 0.805 ROC
Brier score Not specified
Scaled Brier score Not specified

Classification plot

Not specified

Calibration

Regression coefficient 0
Intercept 0
Hosmer-Lemeshow GOF Not specified
 

Calibration plot

Not specified

Histogram

Not specified

Decision curve

Not specified
Comparison
Original study population: 979
Validation study population: 124

Categorical characteristics

Name Subset / Group Nr. of patients Validation P-Value
Breslow thickness ≤1 mm 186 Not available
1.1 - 2.0 mm 380
2.1 - 4.0 mm 252
>4 mm 161
Clark level II/III 156 Not available
IV 724
V 99
Ulceration present No 680 88 0.7571
Yes 299 36
Site of primary tumor Extremity 428 73 0.001
Head and neck 153 21
Trunk 398 30
SLN Negative 821 99 0.2508
Positive 158 25
AJCC clinical stage IA 49 Not available
IB 438
IIA 227
IIB 165
IIC 100

Continuous characteristics

Name LL Q1 Median Q3 UL Unit
Original Validation Age

56


years
Original Validation Breslow thickness

1.8


mm
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