Evidencio validations - Evidencio
Validation of a nomogram to predict the presence of sentinel lymph node metastases in melanoma.
The nomogram is a useful diagnostic tool that provides an adequate accurate prediction of the probability of sentinel lymph node metastases in patients with cutaneous melanoma.
Research authors: Antonio Piñero, Manuel Canteras, Eduardo Ortiz , Enrique Martínez-Barba, Pascual Parrilla
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Discrimination

Rows included 0
C-index 0.869 ROC
Brier score Not specified
Scaled Brier score Not specified

Classification plot

Not specified

Calibration

Regression coefficient 0.953
Intercept 0
Hosmer-Lemeshow GOF Not specified
 

Calibration plot

Histogram

Not specified

Decision curve

Not specified
Comparison
Original study population: 979
Validation study population: 218

Categorical characteristics

Name Subset / Group Nr. of patients Validation P-Value
Breslow thickness ≤1 mm 186 99 Not available
1.1 - 2.0 mm 380 50
2.1 - 4.0 mm 252 54
>4 mm 161 15
Clark level II/III 156 Not available
IV 724
V 99
Ulceration present No 680 172 Not available
Yes 299 46
Site of primary tumor Extremity 428 94 Not available
Head and neck 153 24
Trunk 398 100
SLN Negative 821 178 Not available
Positive 158 40
AJCC clinical stage IA 49 Not available
IB 438
IIA 227
IIB 165
IIC 100

Continuous characteristics

Name LL Q1 Median Q3 UL Unit
Original Validation Age

56
52


years
Original Validation Breslow thickness

1.8
1.19


mm
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