Internal validation of the model predicting surgical site infection after instrumented spine surgery in adults
Internal validation was performed using standard bootstrapping techniques to penalize the model regression coefficients. 
Research authors: Daniël M.C. Janssen, Sander M.J. van Kuijk, Boudewijn d'Aumerie, Paul Willems
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Discrimination

Rows included 0
C-index 0.72 ROC
Brier score Not specified
Scaled Brier score Not specified

Classification plot

Not specified

Calibration

Regression coefficient 0
Intercept 0
Hosmer-Lemeshow GOF Not specified
 

Calibration plot

Histogram

Not specified

Decision curve

Not specified
Comparison
Original study population: 898
Validation study population: 898

Categorical characteristics

Name Subset / Group Nr. of patients Validation P-Value
ASA ASA 1 310 Not available
ASA 2 435
ASA 3 150
ASA 4 3
Diagnosis Trauma 199 Not available
Adult spinal deformity 113
One- or two-level degenerative spinal disorder with neurologic compromise 379
Malignancy 42
Failed back surgery syndrome 96
One- or two-level degenerative spinal disorder without neurologic compromise 61
Spondylodiscitis 8
Co-morbidity Cardiac pathology 49 Not available
Diabetes 73
Rheumatic disease 20
None 756
Previous operation No 645 Not available
Yes 253
Cage No 520 Not available
Yes 378
Dural tear No 807 Not available
Yes 91
Combined anterior approach No 873 Not available
Yes 25
Smoking No 613 Not available
Yes 285
Alcohol No 564 Not available
Yes 334
Blood transfusion No 617 Not available
Yes 281
Using NSAIDs preoperative No 456 Not available
Yes 442

Continuous characteristics

Name Mean SD Unit Plot
Original Validation BMI 26.1
4.7
kg/m2
Original Validation Age 52.2
16.1
years
Original Validation SI score 10.3
5.9
score
Original Validation Blood loss 112
1201
mL
Original Validation Surgical time 248
100
minutes
Original Validation Number of levels fused 3.2
2.9
levels
Original Validation Amount of transfusion 279
675
mL
Original Validation Fraction of inspired oxygen 48.9
12
%
Original Validation Timing antibiotics 37
20
minutes
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