Evidencio validations - Evidencio
Validation cohort from Brigham and Women's Hospital, Harvard Medical School, Boston
Consecutive patients with primary ICH admitted to the neuroscience intensive care unit at Brigham and Women’s Hospital, Harvard Medical School, Boston, were screened for eligibility between January 1, 2010, and June 30, 2012. The same inclusion and exclusion criteria as in the development cohort were applied for patient selection. 
Research authors: Brouwers HB, Chang Y, Falcone GJ, Cai X, Ayres AM, Battey TW, Vashkevich A, McNamara KA, Valant V, Schwab K, Orzell SC, Bresette LM, Feske SK, Rost NS, Romero JM, Viswanathan A, Chou SH, Greenberg SM, Rosand J, and Goldstein JN.
Details
Download

Discrimination

Rows included 0
C-index 0.77
Brier score Not specified
Scaled Brier score Not specified

Classification plot

Not specified

Calibration

Regression coefficient 0
Intercept 0
Hosmer-Lemeshow GOF Not specified
 

Calibration plot

Histogram

Not specified

Decision curve

Not specified
Comparison
Original study population: 817
Validation study population: 195

Categorical characteristics

Name Subset / Group Nr. of patients Validation P-Value
Hypertension Yes 645 Not available
No 172
Antiplatelet use Yes 354 Not available
No 463
Warfarin sodium use Yes 173 40 0.9222
No 644 155
Cerebral amyloid angiopathy Yes 119 Not available
No 698
ICH location Deep 407 96 0.92
Lobar 342 87
Cerebellar 41 8
Brainstem 21 4
Baseline ICH volume <30 ml 565 128 0.042
30-60 ml 156 31
>60 ml 96 36
Intraventricular extension Yes 311 89 0.0606
No 506 106
CT angiography spot sign Yes 74 25 0.1388
No 743 170
In-hospital mortality Yes 193 Not available
No 624
3-months mortality Yes 244 Not available
No 573
Time to initial CT ≤6 hours 357 70 < 0.0001
>6 hours 216 109

Continuous characteristics

Name Mean SD Unit Plot
Original Validation Age 72
71
13
15
years
Name LL Q1 Median Q3 UL Unit
Original Validation Systolic blood pressure
154
179
200

mmHg Invalid Input
Original Validation Glasgow Coma Scale (GCS) score
9
14
15

points Invalid Input
Original Validation White blood cell count
7000
9000
12000

per uL Invalid Input
Original Validation Glucose level
112
134
167

mg/dL Invalid Input
Original Validation Time to initial CT
2.6
3.5
5
5.8
8.3
8.5

hours Invalid Input
Original Validation Baseline ICH volume
7
3
16
7
37
16

mL Invalid Input
Original Validation Intraventricular hemorrhage at baseline
3
9
22

mL Invalid Input
Comments
Comment
Please enter a comment
Comments are visible to anyone

Algorithm feedback

No feedback yet 1 Comment {{ comments.length }} Comments
On {{ comment.created_at }} {{ comment.user.username }} a no longer registered author wrote:
{{ comment.content }}
Evidencio v3.38 © 2015 - 2025 Evidencio. All Rights Reserved