Breast cancer risk in intraductal neoplasms with nipple discharge
Prediction tool to evaluate breast cancer risk in intraductal neoplasms with nipple discharge (c-index: 0.812)
Research authors: Lian ZQ, Wang Q, Zhang AQ, Zhang JY, Han XR, Yu HY et al.
Version: 1.14
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Estimated risk of breast cancer:

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How this model shoud be used: 
This model aids healthcare professionals to evaluate breast cancer risk in patients with intraductal neoplasms with nipple discharge, and thus improve individual risk evaluation and clinical treatment planning.

Overall model performance:
The P-value of the Hosmer-Lemeshow test for the prediction model was 0.36. Area under the ROC curve values (c-indices) of 0.812 (95 % confidence interval (CI) 0.763-0.860) and 0.738 (95 % CI 0.635-0.841) were obtained in the training and validation sets, respectively. The accuracies of the nomogram for breast cancer diagnosis were 71.2 % in the training set and 75.5 % in the validation set.

Model limitations:
The underlying study was limited by the relatively small number of cases and bias associated with the retrospective nature of the study. Further prospective studies are therefore needed to validate the suitability of this nomogram for clinical applications.

Source:
Lian ZQ, Wang Q, Zhang AQ, et al. A nomogram based on mammary ductoscopic indicators for evaluating the risk of breast cancer in intraductal neoplasms with nipple discharge. Breast Cancer Res Treat. 2015;150(2):373-80.

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This model is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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