Robot Prostatectomy Predictors: Pre-Prostatectomy Lymph Node Involvement Calculator // Arnhem
RARP Oncology // Pre-Prostatectomy Lymph Node Involvement Calculator // Arnhem population // 409 (430) PLND patients // Total population 1098 patients // jan 2010  - dec 2017

This model will be presented at the ERUS18 meeting at Marseille 5-7 september

Note: The model is still under development and is therefore not suitable for clinical use.
Research authors: Eelco Collette
Details Formula Study characteristics Files & References
Model author
Model ID
1340
Version
1.9
Revision date
2018-08-03
Specialty
MeSH terms
  • Urology
  • Surgical Oncology
  • Prostatectomy
  • Prostate
  • Prostate Cancer
  • Lymphadenectomy
  • Model type
    Logistic regression (Calculation)
    Status
    public
    Rating
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    Formula
    No Formula defined yet
    Condition Formula

    Additional information

    Input variables
    • iPSA 1,1-90,0
    • cT 1abc 2abc 3ab 
    • BiopsyGGG 1-5

    Missing
    % positive biopsies 3-100

    Predicted outcome
    Positive / negative pelvic lymph node involvement

    Background 
    • Robot Prostatectomy Predictors: Pre-Prostatectomy Lymph Node Involvement Calculator
    • RARP Oncology // Pre-Prostatectomy Lymph Node Involvement Calculator // Rijnstate  population // 409 (430) PLND patients // Total population 1098 patients // jan 2010  - dec 2017
    • The model is still under development and is therefore not suitable for clinical use.
    • Model was validated externally using data from patients treated in Rotterdam

    Study Population

    Total population size: 430
    Males: {{ model.numberOfMales }}
    Females: {{ model.numberOfFemales }}

    Continuous characteristics

    Name Mean SD Unit
    iPSA 15.038 11.0814 ng/ml

    Categorical characteristics

    Name Subset / Group Nr. of patients
    Clinical Tumor Stage cT1abc 116
    cT2abc 232
    cT3ab 63
    Biopsy Gleason Grade Group 1 67
    2 91
    3 103
    4 108
    5 53

    Related files

    No related files available

    Supporting Publications

    The patient has
    ...
    risk of Lymph Node Involvement

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    Result
    Note
    Notes are only visible in the result download and will not be saved by Evidencio

    The patient has risk of Lymph Node Involvement

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    Outcome stratification

    Result interval {{ additionalResult.min }} to {{ additionalResult.max }}

    Conditional information

    Result interpretation

    ROBOT PROSTATECTOMY PREDICTORS: PRE-PROSTATECTOMY LYMPH NODE INVOLVEMENT CALCULATORR

    Results shows the chance of finding lymph node metastases in prostate cancer patients during pelvic lymph node dissection (PLND) of the Arnhem population 2010 - 2017.

    Worldwide threshold recommendations: 
    - The Dutch Oncoline guideline recommends a threshold of 10%.
    - Dutch high volume Robotic Prostatectomy hopsitals typical use a threshold of 6-7%.
    - The Briganti group recommends a threshold of 5-7%.
    - The EAU guideline recommends to perform an ePLND in patients with a risk of LNI above 5%.
    - The Partin group recommends a threshold of 4%.
    - The NCCN guideline recommends a threshold of 2%

    Future
    - EAU guideline recommends new treshold likely 7% risk of node positivity: Eur. Urol., 2017 vol. 72(4) pp. 632-640.
    - Recently independently confirmed in (yet unpublished) Belgian prospective Be-RALP database.

    {{ file.classification }}

    Calculations alone should never dictate patient care, and are no substitute for professional judgement. See our full disclaimer.

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