Third-generation cephalosporin-resistant enterobacterial bacteraemia (3GCR-E-Bac) in community-onset infection
The prediction score for 3GCR-E-Bac, specifically geared towards the initiation of empirical antibiotic treatment, may improve the balance between inappropriate antibiotics and carbapenem overuse.
Research authors: W.C. Rottier, C.H. van Werkhoven, Y.R.P. Bamberg, J.W. Dorigo-Zetsma, E.M. van de Garde, B.C. van Hees, J.A.J.W. Kluytmans, E.M. Kuck, P.D. van der Linden, J.M. Prins, S.F.T. Thijsen, A. Verbon, B.J.M. Vlaminckx, H.S.M. Ammerlaan, M.J.M. Bonten
Version: 1.7
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The calculated risk for 3GCR-E-Bac in community-onset infection is:

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The current prediction model showed adequate discriminatory power with a C-statistic of 0.775 (95% CI: 0.705-0.839)

Before implementation of this prediction model, prospective external validation is required. The development of the prediction model relied on retrospective patient data available in medical charts. Pragmatic inclusion, and exclusion criteria were used which might not fully reflect intended clinical use. Moreover, potentially relevant predictors such as international travel, animal contact, known colonization in household members, dietary preferences, and colonization pressure in the ward were not collected 

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This model is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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