Essen Stroke Risk Score (ESRS) for predicting combined cardiovascular events
The Essen stroke risk score predicts the 1-year risk of combined cardiovascular events on a 10-point scale.
Research authors: CAPRIE steering committee.
Version: 1.5
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1-year risk of combined cardiovascular events: %

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This model calculates the 1-year risk of combined cardiovascular events on a 10-point scale. It was derived from the data subset of 6341 patients with ischemic stroke in the large-scale Clopidogrel versus Aspirin in Patients at Risk of Ischemic Events (CAPRIE) trial.1,2

The model was validated in patients with recent cerebrovascular events using the data set of the European Stroke Prevention Study II (ESPS-2).3,4 In addition, it was externally validated in the large outpatient population of the REduction of Atherothrombosis for Continued Health (REACH) Registry.5

References:

  1. CAPRIE Steering Committee. A randomised, blinded, trial of Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events (CAPRIE). Lancet.1996;348:1329-1339.
  2. Diener HC, Ringleb PA, Savi P. Clopidogrel for the secondary prevention of stroke. Exp Opin Pharmacother. 2005;6:755-764.
  3. Diener HC, Cunha L, Forbes C, Sivenius J, Smets P, Lowenthal A. European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci. 1996;143:1-13.
  4. Diener HC. Modified-release dipyridamole combined with aspirin for secondary stroke prevention. Aging Health. 2005;1:19-26.
  5. Weimar C, Diener HC, Alberts MJ, et al. The Essen stroke risk score predicts recurrent cardiovascular events: a validation within the Reduction of Atherotrombosis for Continued Health (REACH) registry. Stroke. 2009;40(2)350-4.

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This model is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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