Result interpretation:
In the orignal study by Freter et al. (2005)1 based on 132 elective arthroplasty patients, postoperative delirium occurred in 18 patients (incidence 13.6%). Among arthroplasty patients, having two or more risk factors was associated with an eight-fold increase in the incidence of delirium (chi-square = 6.33, P = 0.01) and with an increased length of stay (9.3 days versus 6.7 days; t = 2.18, P = 0.031).
Overall model performance in original study:1
ROC analysis gave an area under the curve (AUC) of 0.77 (95% CI = 0.64–0.0.87) for the DEAR in predicting delirium. The pre-selected cut-off of two or more risk factors had a sensitivity of 0.61 and a specificity of 0.76. Corresponding negative and positive predictive values were 0.93 and 0.29, respectively.
Overall model performance in validation study:2
In a seperate prospective validation study by Freter et al. (2015) based on 283 patients admitted for surgical repair of hip fracture, the selected cut-off of two or more risk factors had a sensitivity of 0.93 and specificity of 0.68. Corresponding negative and positive predictive values were 0.93 and 0.67, respectively.
References:
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