Intended use:
The ACP index provides an efficient, feasible and accessible approach to establish a hierarchical management system of COVID-19 in the SARS-CoV-2 highly endemic areas where medical resources are extremely limited. It is projected that this approach would benefit a considerable number of patients with COVID-19 by directing the medical resources appropriate for the severity of the disease, and thus reduce the mortality and save the socioeconomic resources.
Background information:
By multivariate cox regression analysis (with back selection), it is found that only patients’ age (hazard ratio [HR], 7.0; 95% CI, 2.1 - 23.5; P =0.002) and elevated CRP (HR, 13.5; 95% CI, 3.1 - 58.0; P <0.001) were independently significant in predicting the 12-day mortality risk. Based upon this observation, ACP index named after the Age and C-reactive Protein was developed to stratify the mortality risk of patients with COVID-19.
Source:
Lu J, Uh S, Fan R, Liu Z, Yin x et al. ACP risk grade: a simple mortality index for patients with confirmed or suspected severe acute respiratory syndrome coronavirus 2 disease (COVID-19) during the early stage of outbreak in Wuhan, China (Preprint).
This model is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.
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