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Model performance:
In the original study popuation (N=171), a total of 41 (24,0%) diabetic patients had a recurrent ulcer suggested to be the result of unrecognized repetitive trauma. The optimal probability cutoff point of P = 0.063 yielded a 76% sensitivity (correctly classifying the group with ulcer recurrence) and 51% specificity (correctly classifying the group without ulcer recurrence) for this model.
Model development:
This model was based on univariate and multivariate multilevel logistic regression analysis of 41 ulcer recurrences suggested to be the result of unrecognized repetitive trauma. In the multivariate analysis, having a minor lesion at entry (OR 10.95 [95% CI 5.01–23.96]), a combination of in-shoe peak pressure <200 kPa and adherence >80% (0.43 [0.20–0.94]), a higher barefoot peak pressure (1.11 [1.00–1.22]), and more day-to-day variation in stride count (0.91 [0.86–0.96]) remained independently significantly related to ulcer recurrence.
Source:
Waaijman R, de Haart M, Arts ML, Wever D, Verlouw AJ, Nollet F, Bus SA. Risk factors for plantar foot ulcer recurrence in neuropathic diabetic patients. Diabetes Care. 2014;37(6):1697-1705.
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