MONACO prediction tool: Survival after Resection of Malignant Peripheral Ne - Evidencio
MONACO prediction tool: Survival after Resection of Malignant Peripheral Nerve Sheath Tumours
MONACO is a simple, practical clinical tool for accurately predicting overall survival in patients with primary, resectable malignant peripheral nerve sheath tumours (MPNST) after curative treatment.  
Research authors: I. Acem, E.W. Steyerberg, M. Spreafico, D.J. Grünhagen, D. Callegaro, R.J. Spinner, C.A. Pendleton, J.H. Coert, R. Miceli, G. Abruzzese, Uta E. Flucke, Willem-Bart M. Slooff, Thijs van Dalen, Lukas B. Been, Han J. Bonenkamp, Monique H.M.E. Anten, Martijn P.G. Broen, Marc H.A. Bemelmans, Jos A.M. Bramer, Gerard R. Schaap, Arthur J. Kievit, Jos van der Hage, Winan J. van Houdt, M.A.J. van de Sande, A. Gronchi, C. Verhoef, E. Martin
Version: 2.0
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Internal-external cross-validation by seven different regions was performed to evaluate the performance of the model. Model calibration and discrimination were assessed graphically and by a c-index, respectively. The C-index for the final model was 0.73 (95% CI 0.69-0.77) and the calibration at 5-year overall survival was considered adequate.Cross-validation yield a poled C-index of 0.69 (95% CI 0.65-0.73), with a reasonable calibration across the regions. 
 

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