MSKCC Nomogram: Probability of lymph node involvement in prostate cancer pa - Evidencio
MSKCC Nomogram: Probability of lymph node involvement in prostate cancer patients (includes biopsy cores)
Calculates the probability that prostate cancer has spread to the pelvic lymph nodes (c-index: 0.86). This model includes biopsy cores. 

Disqualifying treatments: This model does not apply to patients who underwent preoperative hormone- or radiation therapy for prostate cancer. 
Research authors: Source: Memorial Sloan Kettering Cancer Center (US)
Version: 2.15
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  • Oncology
  • Logistic regression
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Preoperative PSA

0.1
100
ng/mL

Primary biopsy Gleason grade

Secondary biopsy Gleason score

Clinical tumor stage

Negative biopsy cores

0
20
cores

Positive biopsy cores

0
20
cores

The calculated probability of lymph node involvement is: ...

Set all parameters to calculate prediction.


How this model should be used:
This model calculates the probability that prostate cancer has spread to the pelvic lymph nodes. The model does not apply to patients who underwent preoperative hormone- or radiation therapy for prostate cancer. 

Model performance: 
A validation was performed to assess the discriminative power of the model. On the website of the MSKCC, a c-index of 0.86 is reported. No specific details regarding the validation process are disclosed.

Alternative models: 
For cases in which the number of cores taken at biopsy is unknown, an alternative prediction model that does not require this information is available, although addition of biopsy core information did not improve the discriminative power of the model (c-index 0.86 in both models).


Source: Memorial Sloan Kettering Cancer Center.

This algorithm is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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2 Comments
On 2018-02-11 18:14:45 sbstrum wrote:
nomogram results are identical to MSK (Memorial Sloan Kettering) website: http://www.mskcc.org/mskcc/html/10088.cfm using PSA 2, clinical stage (CS) T1c, & Gleason score (3,4) with 4/16 biopsies positive. Evidencio result = 2 vs MSK = 2. <br /> <br /> Note that MSK site gives all results at once versus having to do separate calculations.
On 2018-03-15 14:53:40 sbstrum wrote:
Look forward to seeing all of the lymph node involvement nomograms tied into an output that shows the different results in a bar graph. Note also that there is a artificial neural net (ANN) for nodal involvement at http://www.prostatecalculator.org.
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