Overall survival in patients with idiopathic pulmonary fibrosis - Evidencio
Overall survival in patients with idiopathic pulmonary fibrosis
Predicts survival time in patients with interstitial pulmonary fibrosis. The model supports clinicians with providing prognostic information to their patients with IPF and to improve the selection of the most appropriate patients for lung transplantation or other standard or novel therapeutic interventions.
Research authors: King TE, Tooze JA, Schwarz MI, Brown KR, Cherniack RM
Version: 1.14
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  • Pulmonology
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How this model should be used:
This model was developed to estimated survival time in patients with idiopathic pulmonary fibrosis (IPF). In addition, the authors demonstrated that the model correlated with the extent and severity of the important histopathologic features of IPF: fibrosis, cellularity, the granulation/connective tissue, and the total pathologic derangement.

Influence of cigarette smoking on survival in IPF: 
Interestingly, in the derivation study by King et al (2001), survival was found to be extended in patients with IPF who are cigarette smokers at the time of their initial evaluation when compared with former smokers or never smokers. The explanation for this phenomenon is unclear. 

Sources:
King TE Jr1, Tooze JA, Schwarz MI, et al. Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model. Am J Respir Crit Care Med. 2001;164(7):1171-81.

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This algorithm is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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