Risk of in-hospital mortality in hemodynamically stable patients with pulmonary embolism
This model calculates the risk of in-hospital mortality in hemodynamically stable patients with pulmonary embolism. It can be used to stratify patients into different risk categories for in-hospital mortality.
Research authors: Volschan A, Albuquerque D, Tura BR, Knibel M, Esteves JP, Bodanese LC, Silveira F, Pantoja J, Souza PC, Mansur J, Mesquita ET, and the Estudo Multicêntrico de Embolia Pulmonar (EMEP) investigators.
Details Formula Study characteristics Files & References
★★★
Model author
Model ID
595
Version
1.21
Revision date
2020-03-06
Specialty
MeSH terms
  • Pulmonary Embolism
  • Risk
  • In-Hospital Mortality
  • Hemodynamics
  • Model type
    Linear model (Calculation)
    Status
    public
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    Formula
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    Condition Formula

    Additional information

    Prospective multicenter chort study of 582 consecutive patients admitted in emergency units or intensive care units with clinically suspected pulmonary embolism and whose diagnosis was confirmed by one or more f the following tests: pulmonary arteriography, spiral CT angiography, magnetic resonance angiography, Doppler echocardiography, pulmonary scintigraphy, or venous duplex scan. Data on demographics, comorbidities and clinical manifestations were collected and included in a logistic regression analysis so as to build the prediction model. 

    Source:
    Volschan A, Albuqerque D, Tura BR, Knibel M, Esteves JP, Bodanese LC, et al. Predictors of hospital mortality in hemodynamically stable patients with pulmonary embolism. Arq Bras Cardiol. 2009;93(2):135-40.

    Study Population

    Total population size: 582
    Males: {{ model.numberOfMales }}
    Females: {{ model.numberOfFemales }}

    Categorical characteristics

    Name Subset / Group Nr. of patients
    Age >65 years Yes 391
    No 191
    Previous history of DVT/PE Yes 102
    No 480
    Abdominal/pelvic surgery Yes 59
    No 523
    Hip/LL fracture yes 39
    Neoplasia Yes 127
    No 455
    Bed rest >72 h Yes 194
    No 388
    Chronic cor pulmonale Yes 40
    No 542
    Cigarette smoking Yes 97
    No 485
    Heart failure Yes 88
    No 494
    Stroke Yes 33
    No 549
    Chest pain Yes 272
    No 310
    Sinus tachycardia Yes 232
    No 350
    Syncope Yes 32
    No 550
    Dyspnea Yes 455
    No 127
    Tachypnea Yes 365
    No 117
    Fever Yes 61
    No 521
    Cough Yes 133
    No 449
    Cyanosis Yes 71
    No 511
    Hemoptisis Yes 36
    No 546

    Total risk score:
    ...
    points

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    Result
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    Total risk score: points

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    Outcome stratification

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    Conditional information

    Result interpretation

    Result interpretation
    In the study group consisting of 582 hemodynamically stable patiens admitted in emergency units or intensive care units with clinically suspected pulmonary embolism, overall in-hospital mortality was 14.1%. After risk stratification, mortalities of 5.4%, 17.8%, and 31.3% were found in the low, moderate and high-risk subgroups, respectively.

    Model performance
    The model showed 65.5% sensitivity and 80% specificity. The discriminative power of the model was considered adquate with an area under the curve (c-index) of 0.77. 

    Source:
    Volschan A, Albuqerque D, Tura BR, Knibel M, Esteves JP, Bodanese LC, et al. Predictors of hospital mortality in hemodynamically stable patients with pulmonary embolism. Arq Bras Cardiol. 2009;93(2):135-40.

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    Calculations alone should never dictate patient care, and are no substitute for professional judgement. See our full disclaimer.

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