5-year survival after resection of perihilar cholangiocarcinoma - Evidencio
5-year survival after resection of perihilar cholangiocarcinoma
This validated prognostic nomogram predicts the 5-year disease-specific survival (DSS) after a curative intent resection of perihilar cholangiocarcinoma 
(c-index: 0.72).
Research authors: Groot Koerkamp B, Wiggers JK, Gonen M, Doussot A, Allen PJ, Besselink MGH, Blumgart LH, Busch ORC, D'Angelica MI, De Matteo RP, Gouma DJ, Kingham TP, van Gulik TM, Jarnagin WR
Version: 1.6
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Estimated 5-year disease-specific survival:

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How this model should be used:
This model calculates the predicted 5-year disease-specific survival (DSS) after a curative intent resection of perihilar cholangiocarcinoma (PCH).

Model performance: 
External model validation was based on a prospectively maintained database consisting of 133 patients with confirmed PCH from the Academic Medical Center (AMC, Amsterdam, The Netherlands). Assessment of model discrimination resulted in a concordance index of 0.72, compared with 0.60 for the AJCC staging system. Calibration in the validation cohort (figure 1) showed that the model tends to underestimate DSS in low and intermediate risk groups (i.e. patients had a better median DSS than predicted by the model).

Reference:
Groot Koerkamp B, Wiggers JK, Gonen M, et al. Survival after resection of perihilar cholangiocarcinoma-development and external validation of a prognostic nomogram. Ann Oncol. 2015;26(9):1930-5.

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This algorithm is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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