1-year survival: Colorectal Peritoneal Metastases Prognostic Surgical Score (COMPASS)
A prognostic nomogram to predict 1-year overall survival in patient with colorectal peritoneal metastases treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherpy (HIPEC).
Research authors: Simkens GA, van Oudheusden TR, Nieboer D, Steyerberg EW, Rutten HJ, Luyer MD, Nienhuijs SW, and de Hingh IH.
Version: 1.11
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Estimated 1-year survival after CRS and HIPEC:

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How this model should be used:
This model predicts 1-year survival in patients with colorectal peritoneal metastases treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). 

Model performance: 
The COMPASS model differentiated well and showed a Harrell's c statistic of 0.72 with a calibration plot showing good agreement. The overall performance of the COMPASS as assessed with the explained variation (Nagelkerke R2 statistic) was 0.19.

Context information:
External validation of an alternative prediciton model (peritoneal surface disease severity score; PSDSS) was performed for the same dataset (200 patients with colorectal peritoneal metastasis treated with CRS + HIPEC). Discrimination of the PSDSS model was suboptimal with a Harrell's c statistic of 0.62.

Source: 
Simkens GA, van Oudheusden TR, Nieboer D, et al. Development of a Prognostic Nomogram for Patients with Peritoneally Metastasized Colorectal Cancer Treated with Cytoreductive Surgery and HIPEC. Ann Surg Oncol. 2016;23(13):4214-4221.

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This model is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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