Winter nomogram: Predicting lymph node involvement through sentinel guided - Evidencio
Winter nomogram: Predicting lymph node involvement through sentinel guided pelvic lymph node dissection (SPLND)
Existing nomograms predicting lymph node involvement (LNI) in prostate cancer (PCa) are based on conventional lymphadenectomy. The aim of the study was to develop the first nomogram for predicting LNI in PCa patients undergoing sentinel guided pelvic lymph node dissection (sPLND).
Research authors: Alexander Winter, T. Kneib, M. Rohde, R.P. Henke, F. Wawroschek
Version: 1.14
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According to the internal validation, a 7% threshold would be regarded as the most favorable cutoff. In our population of 1,296 patients, 406 patients (31.3%) were classified below this threshold. Avoidance of sPLND in those 406 cases would have resulted in missing LNI in 7 patients or in 3% of all patients with histologically confirmed LNI. Therefore, approximately one-third of patients could be spared from sPLND. Considerable costs and patient discomfort could be saved. 

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