Extent of Pelvic Lymph Node Dissection and the Impact of Standard Template Dissection on Nomogram Prediction of Lymph Node Involvement
Lymph node dissection is an important oncologic component of the radical prostatectomy procedure, and its role in staging and as a therapeutic intervention has been the focus of renewed interest. The presence of lymph node metastasis is associated with an elevated risk of systemic dissemination of disease and death. Additional diagnostic and therapeutic benefits have been recognized when performing lymph node dissection adjunctively during radical prostatectomy. This nomogram is an updated version of the nomogram described by Cagiannos et al (2003). 
Research authors: Guilherme Godoy, Kian Tai Chong, Angel Cronin, Andrew Vickers, Vincent Laudone, Karim Touijer, Bertrand Guillonneau, James A. Eastham, Peter T. Scardino, Jonathan A. Coleman
Details Formula Study characteristics Files & References
Model author
Model ID
Revision date
MeSH terms
  • Nomograms
  • Lymph Node Dissection
  • Cancer of Prostate
  • Prostate Specific Antigen
  • Gleason Score
  • Lymph Nodes
  • Model type
    Logistic regression (Calculation)
    No Formula defined yet
    Condition Formula

    Additional information

    No additional information available

    Study Population

    Total population size: 3721
    Males: {{ model.numberOfMales }}
    Females: {{ model.numberOfFemales }}

    Continuous characteristics

    Name LL Q1 Median Q3 UL Unit
    Age at surgery 54 59 64 Years
    Total PSA 4.00 5.31 7.33 ng/ml
    No. of nodes removed 7 11 16 Nodes

    Categorical characteristics

    Name Subset / Group Nr. of patients
    Type of surgery Open 2786
    Laparoscopic/robotic 935
    Clinical stage T1 2372
    T2a 741
    ≥T2b 608
    Biopsy Gleason grade ≤6 2024
    7 1398
    ≥8 299
    Pathologic gleason grade ≤6 1190
    7 2257
    ≥8 238
    Extracapsular extension 3622
    Seminal vesicle invasion 219
    Positive surgical margin 480
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    The calculated risk for lymph node involvement is:

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    The calculated risk for lymph node involvement is:

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    Outcome stratification

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    Result interpretation

    In the decision-curve analysis, this nomogram is able to provide the best net benefit for all probabilities below the threshold probability of 6%

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