Risk of venous thromboembolism in hospitalized patients (Padua prediction score)
The Padua prediction score determines the risk of developing a venous thromboembolism (VTE) in patients who are hospitalized and have risk factors for developing VTE, therewith identifying patients who might benefit from anticoagulation.
Research authors: Barbar S, Noventa F, Rossetto V, Ferrari A, Brandolin B, Perlati M, De Bon E, Tormene D, Pagnan A, and Prandoni P.
Version: 1.35
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Padua prediction score: points

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Context information: 
The Padua prediction score aims to improve stratification of the thromboembolic risk in hospitalized medical patients compared with usual practise.1 The risk score identifies those medical conditions for which international guidelines strongly recommend thromboprophylaxis.2

Model restrictions:
Before being applicable for general application, the Padua prediction score still requires proper confirmation and validation from other large prospective studies. In addition, whether the awareness of the potential value of the Padua prediction score can induce a higher rate of physicians to adopt proper thromboprophylaxis in their patients remains to be demonstrated. 

Imporant remarks:

  • The Padua prediction score is meant to risk stratify patients who have a potential risk for VTE, not to diagnose VTE.
  • If deemed appropriate, anticoagulation should not be withheld from patients who require it as part of the treatment for their diagnosis.
  • Prior to initiating any anticoagulant therapy a patient’s bleeding risk should be evaluated using appopriate risk scores. 
  • The Padua prediction risk score was not assessed for patients with contraindications for antithrombotic drugs, because they were excluded from the study. 
Sources:
  1. Barbar S, Noventa F, Rossetto V, et al. A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score. J Thromb Haemost. 2010;8(11):2450-7.
  2. Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133(Suppl. 6): 381–453.

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