Predicting the risk of Ipsilateral extraprostatic extension - Evidencio
Predicting the risk of Ipsilateral extraprostatic extension
Development and External Validation of a Biopsy -Derived Nomogram to Predict Risk of Ipsilateral Extraprostatic Extension

Given that at least 20% of patients currently undergoing Radical Prostatectomy (RP) for presumed localized disease are noted to have ExtraProstatic Extension(EPE), accurate prediction of preoperative EPE risk remains a clinical need to help surgeons better select patients for a nerve-sparing versus non-nerve sparing approach. Although previous attempts have been made to predict risk of EPE using pre -operative markers, a model with improved predictive accuracy and generalizability/external validity is still needed. In this report, we used a number of preoperative markers to develop, and subsequently externally validate, a nomogram that predicts risk of side-specific EPE at time of surgery.
Research authors: Rashid Sayyid, Nathan Perlis, Ardalanejaz Ahmad, Andrew Evans MD, Ants Toi, Michael Horrigan, Antonio Finelli, Alexandre Zlotta, Girish Kulkarni, Robert Hamilton, Christopher Morash, Neil Fleshner
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Calculated risk for extraprostatic extension

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Calculationed risk may be used to assist surgical decision-making prior to radical prostatectomy

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