INFLUENCE: risico op locoregionaal recidief bij patiënten met borstkanker in jaar 3
Berekent het risico op een locoregionaal recidief (LRR) bij patiënten met borstkanker in jaar 3 (c-index: 0.70).
Research authors: Annemieke Witteveen, Ingrid M. Vliegen, Gabe S. Sonke, Joost M. Klaase, Maarten J. IJzerman, and Sabine Siesling.
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Het risico op een lokaal recidief in jaar 3 bedraagt:

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Beoogde toepassing INFLUENCE predictiemodel: 
Dit model kan worden ingezet als instrument om borstkanker patiënten met een hoog risico op een locoregionaal recidief te identificeren. Op basis hiervan kan een inschatting worden gemaakt ten aanzien van de gewenste intensitieit van follow-up. 

Model prestaties: 
Het oppervlak onder de ROC-curve bleek bij externe validatie 0.70 te bedragen. De discriminatie van het model wordt daarmee adequaat geacht. 

Witteveen A, Vliegen IM, Sonke GS et al. Personalisation of breast cancer follow-up: a time-dependent prognostic nomogram for the estimation of annual risk of locoregional recurrence in early breast cancer patients. Breast Cancer Res Treat. 2015; 152(3): 627–636.

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