HAS-BLED Score for Major Bleeding Risk
Estimates the 1-year risk for major bleeding in patients with atrial fibrillation (c-statistic: 0.72).
Research authors: Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJ, Lip GY.
Version: 1.18
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  • Internal medicine
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Individual HAS-BLED risk score:

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The HAS-BLED score estimates the risk of major bleeding for patients on anticoagulation for atrial fibrillation.

About this model:
The HAS-BLED bleeding risk score was first described in 2010 and is recommended in European and Canadian guidelines to estimate major bleeding risk. In 2011, the Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) study group described a new bleeding risk scheme for AF (including five weighted risk factors: anemia, severe renal disease, age ≥ 75 years, previous hemorrhage, and diagnosed hypertension).

Model performance:
In a validation study by Roldan et al (2013), the HAS-BLED score showed significantly better prediction accuracy than the ATRIA score (c-statistic 0.68 vs 0.59, respectively; P = 0.035). 
In a study by Lip et al (2011) including 7,329 patients with AF, the c-index for the HAS-BLED score was found to be 0.67.

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This model is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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