Basaalmetabolisme (Mifflin formule) in kilocalorieën per dag
Geschat basaalmetabolisme in kcal/dag gebaseerd op de studie van Mifflin et al (1990). 
Research authors: Mifflin MD, St Jeor ST, Hill LA, Scott BJ, Daugherty SA, and Koh YO.
Details Formula Study characteristics Files & References
Model author
Model ID
Revision date
MeSH terms
  • Metabolic Rate, Basal
  • Basal Metabolic Rate
  • Model type
    Custom model (Conditional)
    Condition Formula

    Additional information

    A predictive equation for resting energy expenditure (REE) was derived from data from 498 healthy subjects, including females (n = 247) and males (n = 251), aged 19-78 y (45 +/- 14 y, mean +/- SD). Normal-weight (n = 264) and obese (n = 234) individuals were studied and REE was measured by indirect calorimetry. Multiple-regression analyses were employed to drive relationships between REE and weight, height, and age for both men and women.

    Study Population

    Total population size: 498
    Males: {{ model.numberOfMales }}
    Females: {{ model.numberOfFemales }}

    Additional characteristics

    No additional characteristics defined
    Basaalmetabolisme (Mifflin formule) in kilocalorieën per dag
    Refer to Intended Use for instructions before use
    Evidencio B.V., Irenesingel 19, 7481 GJ, Haaksbergen, the Netherlands
    Notes are only visible in the result download and will not be saved by Evidencio

    Geschat basaalmetabolisme (Mifflin formule): kcal/dag

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    Outcome stratification

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    Conditional information

    Result interpretation

    Geschat basaalmetabolisme in kcal/dag gebaseerd op de studie van Mifflin et al (1990) in 494 patiënten. Deze formule presteert met name goed in patiëntne met ondergewicht (BMI < 18.5 kg/m2).

    Hoe dit model kan worden gebruikt:
    Om onder- of overvoeding te voorkomen, dient de calorische intake te worden afgestemd op de energiebehoefte van de individuele patiënt. Het gebruik van formules om de individuele energiebehoefte te schatten heeft daarmee de voorkeur boven het aanhouden van een vaste calorische intake (bijvoorbeeld 30 kcol/kg) per patiënt. 

    In een retrospectieve validatie studie verricht tussen juli 2002 en april 2005 door Weijs et al., werden 18 verschillende formules voor het berekenen van het basaalmetabolisme geëvalueerd. In totaal werden 48 polikliinische en 45 klinische patiënten geïncludeerd voor wie indirecte calorimetrische data beschikbaar was. Daarnaast werd een subgroep van 42 patiënten met ondergewicht BMI < 18.5 kg/m2) geanalyseerd. Van alle geëvalueerde formules, gaf de FAO/UNU/WHO vergelijking de beste schatting met een afwijking van 182, 277 en 219 kcal/dag voor respectievelijk poliklinische, klinische patiënten en patiënten met ondergewicht. De gereviseerde Harris & Bennedict formule bleek een goed alternatief. De Mifflin formules presteerde met name goed bij patiënten met ondergewicht.


    1. Weijs PJ, Kruizenga HM, van Dijk AE, et al. Validation of predictive equations for resting energy expenditure in adult outpatients and inpatients. Clin Nutr. 2008;27(1):150-7.
    2. FAO/WHO/UNU. Energy and protein requirements. WHO technical report series. Geneva; 1985.
    3. Roza AM, Shizgal HM. The Harris Benedict equation reevaluated: resting energy requirements and the body cell mass. Am J Clin Nutr. 1998;40:168-82.
    4. Mifflin MD, St Jeor ST, Hill LA et al. A new predictive equation for resting energy expenditure in healthy individuals. Am J Clin Nutr. 1990;51:241-7.

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